NAD+ cream is a topical formulation containing NAD+ (Nicotinamide Adenine Dinucleotide) designed for direct application on the skin. The primary uses of NAD+ cream include:

1. Skin rejuvenation: NAD+ cream may help promote skin cell regeneration, improving overall skin health and appearance.
2. Anti-aging effects: By replenishing NAD+ levels in the skin, the cream may help combat visible signs of aging, such as wrinkles, fine lines, and age spots.
3. Skin barrier support: NAD+ cream can contribute to maintaining a healthy skin barrier, improving hydration and protecting against environmental stressors.
4. Boosting cellular repair: NAD+ plays a crucial role in DNA repair and cell maintenance. The cream may support these processes in the skin cells.

The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

NAD+ supplements can have side effects, some of the most common include:

1. Nausea: Some people may experience feelings of nausea when taking NAD+ supplements, especially if they take higher doses than recommended.
2. Headaches: NAD+ supplements can cause headaches, particularly if you are sensitive to nicotinic acid (the component of NAD+ that gives niacin its name).
3. Flushing: NAD+ supplements can cause flushing, a sensation of warmth and redness in the skin, especially when taken on an empty stomach.
4. Diarrhea: NAD+ supplements can cause diarrhea, especially if taken in high doses.
5. Dizziness: NAD+ supplements can cause dizziness, especially in people who are prone to this symptom.

It is important to note that these side effects are usually mild and do not last long. If you experience any adverse effects when taking NAD+ supplements, you should stop taking them and connect to your healthcare provider via IVY RX messaging portal.

To apply NAD+ cream, follow these simple steps:

1. Cleanse your skin: Begin by gently cleansing your face and neck with a mild cleanser to remove any dirt, oil, or makeup. Pat your skin dry with a soft towel.
2. Apply a small amount: Take a small amount of NAD+ cream, approximately the size of a pea, onto your fingertips.
3. Distribute evenly: Gently dot the cream across your face and neck, ensuring even distribution.
4. Massage gently: Using your fingertips, massage the cream into your skin using upward, circular motions. Be gentle around the delicate eye area and avoid direct contact with your eyes.
5. Allow absorption: Allow the cream to fully absorb into your skin for a few minutes before applying other skincare products or makeup.

Patients may notice improvements in skin hydration, texture, and overall appearance within a few days to a few weeks of consistent use. The cream may help reduce fine lines, wrinkles, and other signs of aging over time with continued application.

MedMan Compounded Semaglutide & Tirzepatide Treatment Guide
Advanced GLP-1 Therapies for Weight Management & Metabolic Support

Please Note: Compounded medications, including compounded semaglutide and tirzepatide, may be prescribed by licensed physicians but are not FDA-approved. FDA-approved versions of semaglutide are available and may be considered as alternatives. Compounded medications are not reviewed by the FDA for safety, effectiveness, or manufacturing quality.

⚠️ Important Safety Warnings
Seek immediate in-person medical care or contact your doctor if you experience any of the following:

Severe nausea, vomiting, or dehydration
Stay well-hydrated to avoid complications, especially if experiencing gastrointestinal symptoms.

Kidney issues or kidney failure
Vomiting and diarrhea may worsen kidney problems in those with pre-existing conditions. Dehydration may require hemodialysis.

Signs of thyroid cancer (Thyroid C-Cell Tumor)
Look out for hoarseness, difficulty swallowing, neck swelling, or shortness of breath. (See Black Box Warning below.)

Pancreatitis
Severe abdominal or back pain that does not go away may indicate inflammation of the pancreas.

Gallbladder disease
Symptoms include upper abdominal pain, fever, yellowing of the eyes or skin, nausea/vomiting. Further evaluation may be required.

Hepatitis or liver issues
Includes jaundice or elevated liver enzymes.

Diabetic retinopathy
Vision changes in those with type 2 diabetes, especially those with prior eye complications.

Severe gastrointestinal disease
Avoid use if you have a history of serious gastrointestinal disorders.

Low blood sugar (hypoglycemia)
Rare with GLP-1s, but possible when combined with insulin or sulfonylureas. Symptoms: shakiness, dizziness, confusion, slurred speech, sweating, anxiety, or fainting.
Immediate Action: Consume 15–20g of sugar (e.g., juice, candy, soda).

Increased heart rate

Worsening depression, mood changes, or suicidal thoughts

Allergic reactions
Swelling of the face, lips, throat; rash, itching, trouble breathing, rapid heartbeat, or fainting.

⚠️ Never share your compounded semaglutide or tirzepatide with others.

💊 Drug & Supplement Interactions
Alcohol & Medication Interactions
Avoid alcohol. Compounded semaglutide may interact with both prescription and over-the-counter medications.

Gastrointestinal Effects on Oral Drugs
Delays gastric emptying and may affect absorption of oral medications.

Hormonal Medications
If taking thyroid or hormonal medications, consult your prescribing doctor to adjust timing.

Narrow Therapeutic Drugs (e.g., Warfarin)
Monitor drug levels closely under medical supervision.

🧬 BLACK BOX WARNING – Thyroid C-Cell Tumors
GLP-1 receptor agonists like semaglutide and tirzepatide are contraindicated in patients with:

Personal or family history of medullary thyroid carcinoma

Multiple endocrine neoplasia syndrome type 2 (MEN 2)

In animal studies, GLP-1 drugs have caused thyroid tumors. It is unknown if this risk applies to humans.
Contact your physician immediately if you experience:

Neck swelling or lumps

Hoarseness

Difficulty swallowing

Shortness of breath

👩‍⚕️ Precautionary Guidance
Consult your healthcare provider before beginning treatment. Share your full medical history.

Avoid use if pregnant, planning pregnancy, or breastfeeding.
Discontinue use at least 2 months prior to attempting conception.
These medications may cause fetal harm.

Use adequate contraception while on this therapy.

Notify your provider if you have any kidney, liver, pancreas, or thyroid concerns.

📞 What To Do in Case of Emergency
Call 911 or visit your nearest emergency room immediately for medical emergencies.

To report adverse events or reactions, contact the FDA at 1-800-FDA-1088 or submit a report at www.fda.gov/medwatch.

📌 Legal & Safety Disclaimers
This product is compounded in the United States and prescribed as part of a physician-guided program.
All compounded medications are custom-mixed by a licensed pharmacy but are not evaluated by the FDA.
Statements provided are not intended to diagnose, treat, cure, or prevent any disease.

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